Study Overview: Curcumin and Blood Pressure Title: Antihypertensive Effects of Curcumin/Turmeric Supplementation in Prediabetes and Diabetes: A Systematic Review and Meta-Analysis of Randomised Controlled Trials
Date: Published August 2025
Location: Multicenter study involving researchers from Iran (Mashhad, Kermanshah, Tehran, Shiraz) and the United Kingdom (Chester).
Key Results
This meta-analysis of 15 randomized controlled trials (n=855) evaluated the impact of curcumin on blood pressure in diabetic and prediabetic adults. The findings include:
Systolic Blood Pressure (SBP): Supplementation significantly reduced SBP by an average of 2.69 mmHg.
Hypertensive Subgroup: Participants with baseline SBP ≥130 mmHg saw a larger reduction of 3.41 mmHg.
Diastolic Blood Pressure (DBP): No significant overall change was found (p=0.15), though a significant reduction was noted specifically in the Type 2 Diabetes subgroup.
Efficacy Factors: Enhanced results were observed with nano-curcumin, doses exceeding 1 g/day, and formulations containing piperine.